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Those arrested are senior medical superintendent Dauda Mugoya, senior accountant Micheal Isabirye and hospital administrator Ramathan Mugolofa.
Charles Amanya, 16, refused to die in one of the most shocking tales of torture and burial.
Police introduced a canine sniffer dog, which led them to Sentongo, a witch-doctor who was arrested and detained at Kiboga Police Station.
Witness attributed the accident to speeding by the cattle truck driver, who reportedly lost control when he attempted to avoid a pothole in the middle of road.